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Determination of LongR3-IGF-I, R3-IGF-I, Des13 IGF-I and their metabolites in human plasma samples by means of LCMS

In parallel, the ubiquitination levels of wild-type GLUD1 increased upon AdOx treatment while no significant changes were observed in the R76K mutant (Fig

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Formulators selected hydrochloride salt to mirror the acid-base characteristics of existing diagnostic arginine infusions but buffered the final product to physiological pH to lessen the transient hyperchloremic acidosis sometimes seen with large arginine-only boluses

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