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GLP-1 drugs can affect hydration and blood pressure, which influence kidney function over time

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When bile acid turnover is disrupted, excess bile acids can reach the colon and act as pro-secretory agents while accelerating colonic transit

Mild side effects include: paresthesia (a tingling or pins and needles sensation in the hands and feet) cognitive effects such as: slowed thinking difficulty concentrating or remembering things speech problems, such as slurred speech fatigue sleepiness dizziness nausea weight loss, which is often due to a loss of appetite or changes in how things taste These are just some of the mild side effects of Topamax