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Patients with renal dysfunction are highly susceptible to oxidative stress, as risk factors such as diabetes, renal hypertension, dietary restrictions, hemodialysis, and old age predispose them to increased levels of ROS

Mazilescu, L

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Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: A proof-of-concept exploratory study

Compared to patients with low HCV RNA, viremic patients had a similar incidence of death and liver-related death while patients with high HCV RNA had a significantly increased incidence of death and liver-related death after adjustment (see slides below)