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Notably, ApoE4 secretion was reduced in microglia (30%) compared to astrocytes (50%) (Lanfranco et al., 2021)

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Certain medications use sublingual delivery specifically to bypass first-pass metabolism in the liver

The downside of giving it to a dog who didn't need it: zero

Cagrilintide is designed to be more stable and is lipidated to extend its duration of action