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The loss of neuronal connections in AD brain is basically attributed to disrupted signaling pathways that affect both synaptic plasticity and dendritic functions, the two crucial controllers of cognitive processes

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The analysis was done after the fact rather than as a primary endpoint, and the clocks were measured in blood, so they track systemic aging rather than the brain in particular

In amikacin-treated groups, biofilms were grown in the presence of 418 g/ml amikacin dissolved in TSB