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As of now, these preclinical studies with davalintide represent the only available literature on davalintide and further development of davalintide in humans trials have been discontinued due to lack of superiority to pramlintide on weight loss (128)

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Article last reviewed: April 18, 2026 Next scheduled review: October 15, 2026

While encouraging, these results should be interpreted cautiously given the study's limitations, including its small sample size, short duration, and use of only low doses of semaglutide