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Description

Interestingly, TFAM and mtDNA form a self-regulatory positive feedback loop: TFAM knockout triggers mtDNA depletion, while reduced mtDNA copy numbers further promote TFAM degradation [54,55,56] (Table 1)

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Also, in the second experiment (strain 3D7, see Methods), all RBC samples (index patient and three controls) were efficiently invaded by the parasites

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Typically the dissolving process takes between 6 and 18 months

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