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The mechanism partly resembles that found in the pancreatic beta cell, involving closure of ATP-sensitive potassium (K ATP ) channels [14], but in GLUTag cells an additional depolarising stimulus is provided by electrogenic coupled Na + and glucose entry via sodium-coupled glucose cotransporters [15]

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Molecular and Biochemical Overview AOD-9604 was designed to isolate the lipolytic domain of hGH while excluding regions responsible for insulin-like growth factor-1 (IGF-1) activation