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At JosephCareRX, we prescribe Ozempic not only for its effectiveness in managing type 2 diabetes but also for its additional benefitsreducing cardiovascular risks such as heart attack and stroke in qualifying patients who have existing cardiovascular conditions

For example, the LEADER trial showed that Liraglutide significantly reduced the risk of major adverse cardiovascular events (MACE) by 13% and cardiovascular death by 22% in comparison to placebo

5 Randomized data suggest that intermittent energy restriction achieves similar HbA1c reductions to continuous energy restriction, with no clear between-group differences in GLP-1 concentrations, so any specific GLP-1 benefit of IF remains uncertain

Statistical analysis Analysis was based on non-parametric tests due to low sample sizes in rare clinical outcome groups and to receive more robust information regarding outliers

Butsch also points out that there arent any official or standard guidelines for microdosing semaglutide or tirzepatide, and microdosing isnt endorsed by the American Diabetes Association