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Identification of a small probe that can be conjugated to proteins by proximity labeling

These changes suggest that oxidative stress impacts ECM balance and can contribute to cartilage disorders, such as OA, through different mechanisms than what is usually observed with inflammatory stimulus, offering new insights into the molecular mechanisms underlying oxidative stress in chondrocytes

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Most of the beneficial effect of semaglutide on UACR reduction was mediated by HbA1c, BW and BP reduction 79