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Symptoms such as fatigue, weakness, nausea, vomiting, and swelling of the hands and feet are increasingly probable at this stage, but some patients have no symptoms whatsoever

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ii) a better typing of chronic users to study risks of developing hepatotoxicity at the highest recommended doses (even though this is still controversial there is accumulating evidence that the maximum recommended dose can induce mild-to-moderate hepatic cytolysis)

Retreatment was necessary in 20% of men treated and included either photoselective vaporization of the prostate or TURP.