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Although much of this evidence derives from animal models, making direct extrapolation to humans complex, significant functional commonalities exist between the murine and human BBB, including glucose transport, the presence of circumventricular organs (CVOs), and saturable transport systems [33]

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In December 2024 tirzepatide was approved by the FDA for the treatment of moderate to severe obstructive sleep apnea in adults with obesity

By combining the two drugs, researchers were hoping to preserve muscle mass during weight loss