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The evaluation of RPM supplementation over a 3-month period in rams showed positive effects in increasing serum testosterone and scrotal circumference ( Considering the importance of methionine (MET) as a methyl donor in DNA methylation processes, studies have investigated the effects of RPM supplementation in males on epigenetic regulation, as well as on gene and protein expression profiles related to sperm quality and seminal plasma composition

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Acceso: 4 de febrero de 2026

ALS can also be genetically categorized as being either sporadic ALS (SALS) that represents 9095% of all diagnoses and in which there is no known direct genetic contribution to the disease, or familial ALS (FALS) that makes up the remaining 510% of all cases where known genetic mutations such as in SOD1, TDP-43, FUS, and C9ORF72 predominate (Zarei et al., 2015)