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The SD rats were fed with normal pellet diet (AGRIMAT, Kumasi, Ghana), given water ad libitum , and maintained under standard laboratory conditions (temperature 25C, relative humidity 6070%, and 12 h light-dark cycle)
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Diane-35 is a combination birth control pill that contains 2 active ingredients: cyproterone acetate and ethinyl estradiol
Hence its popularity in skin creams, serums and lotions, all meant for topical application
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