A Comprehensive Review on Weight Gain following Discontinuation of Glucagon-Like Peptide-1 Receptor Agonists for Obesity
And if a patient meets their goalsloses weight, improves blood sugar, blood pressure, or cholesterolwe may even de-escalate therapy by lowering the semaglutide dose or switching to liraglutide to prevent excess weight loss, which can come at the expense of muscle mass. Overall, switching works best when its intentional and coordinated with your physician
Eventually, 374 studies were eligible for inclusion in the review (Extended Data Fig
This action supports healthy weight loss by reducing overall calorie intake and promoting a sense of fullness, making it an important target for medications designed to aid in weight management
Perkovic V, Jardine MJ, Neal B, et al