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Will Lee, a professor of internal medicine at the University of Texas Southwestern Medical Center whose research has shown that acetaminophen is the leading cause of acute liver failure in the U.S., on the drug As McNeil quietly pursued a safer acetaminophen, a bespectacled, bow-tied Dallas doctor named Will Lee was pursuing research that would change the debate about the drug
Gating residues involved in the occluded-to-inward conformational transition of OCTN2 Alternating-access transport by secondary active transporters requires the coordination of gates that enclose or preclude access to the substrate-binding site from either side of the membrane 51
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