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Thus, for longitudinal comparisons between the pretreatment baseline and post-treatment follow-up timepoints, including post-DBS, post-TMS and post-levodopa conditions, one-tailed paired t -tests were used, based on an a priori directional hypothesis that therapeutic STN-DBS, SCAN-targeted TMS and levodopa would reduce the SCAN hyperconnectivity observed in PD
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The N-terminal GSDMD fragment creates transmembrane pores, leading to the initiation of pyroptotic cell death
