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Moreover, GLP-1 analogues cause a reduction in cardiovascular events in non-diabetic individuals [17]

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296:2572-2581 [PubMed: 17101640] 100

In the brains of Alzheimers disease (AD) patients, pathological features such as reduced mitochondrial membrane potential (m), accumulation of mitochondrial peroxides, aberrant opening of the mitochondrial permeability transition pore (mPTP), and mitochondrial iron (mFe) overload are commonly observedeach closely linked to ferroptosis induction (Chen et al., 2023

However, complete responses by multi-kinase inhibitors are virtually uncommon and have many significant adverse effects due to off-target effects, which can lead to poor quality of life