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Blood Pressure and Lipids Both medications produce similar improvements in cardiovascular risk factors: Blood pressure: Both typically reduce systolic BP by 3-6 mmHg Effects are similar between medications Lipids: Both reduce triglycerides Modest effects on LDL cholesterol Similar lipid improvements Metabolic Comparison Cost and Insurance Cost considerations may influence medication choice for some patients

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Fourth, the tirzepatide not working anymore guide addresses what happens when initial results plateau or stop, which can occur regardless of medication source