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B12 supplements are often used to treat or prevent deficiency, which can lead to symptoms such as fatigue, weakness, constipation, loss of appetite, and megaloblastic anemia
That makes it a different and useful tool for studying NAD+ biology
Some longer-term (i.e., when steroids are taken for more than six to 12 months) side effects include diabetes mellitus (poor control of sugar) and osteoporosis (thinning of the bones)
Many patients report that after about 4 weeks of weekly injections, they observe improvements such as more steady energy levels and easier weight loss progress
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