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Following a single oral 100 mg dose to healthy volunteers, mean plasma AUC of sitagliptin was 8.52 Mhr, Cmax was 950 nM, and apparent terminal half-life (t1/2) was 12.4 hours

GLP-1 stimulates insulin secretion, inhibits glucagon secretion, slows gastric emptying, and promotes satiety, all of which contribute to weight loss

Optimal forms of GSH supplementation are still debated

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