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564 HO-1 and GPX4 were downregulated due to Nrf2 defects in astrocytes, leading to increased mitochondrial fragmentation, DNA oxidation, and lipid peroxidation in mouse astrocytes, 564 suggesting that Nrf2 deficiency promotes ferroptosis in astrocytes in AD mice

Nature 1988, 334 (6178), 173175

Managing side effects during dose escalation in units Gastrointestinal side effects peak during dose escalation, not at any specific milligram amount

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