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GLP-1 Agonists Like Semaglutide Show Promise in Reducing Alcohol Use Disorder, Study Finds Feb 20, 2025 2 min read Updated: Nov 6, 2025 Recent research suggests that semaglutide, a medication primarily used for type 2 diabetes and weight management, may also help reduce alcohol consumption

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Hormone therapy is a tool

TRIUMPH-1 trajectory (80 weeks + extension): Week 80: 28.3% average weight loss (2,339 patients) 104-week extension (BMI 35 subgroup): 30.3% average weight loss Weight loss does not plateau at 80 weeks it continues in longer treatment The TRIUMPH-1 104-week extension is the most important long-term efficacy signal we have