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A "Strong" rating indicates support from multiple well-designed trials, "Moderate" suggests promising but less consistent findings, and "Limited" or "Emerging" applies to areas with early-stage, small, or mixed research

The coatomer binds to a C-terminal dibasic retrieval motif, Lys-x-Lys-x-x CT or Lys-Lys-x-x CT (x = any amino acid

doi: 10.1111/gcb.16209 71 SchirrmacherP.RoggatzC

This innovative mechanism of action allows it to not only amplify the insulin release in a glucose-dependent manner but also to reduce the glucagon secretion during high blood sugar levels

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