bcbsm glp 1 Blue Cross Blue Shield of Michigan won't cover popular weight-loss drugs GLP-1 receptor agonists show anti-cancer

They can influence melanin pathways for some users, but results vary by dose, route, skin type, vitamin C use, and sun habits

Cell 137 , 10621075 (2009)

This represents complementary rather than redundant mechanisms

The latest dual-action GLP-1 analogue, tirzepatide , which also affects GIP receptors, was approved in the US in 2022 as the drug Mounjaro for the treatment of type 2 diabetes, and in 2023 as Zepbound for the treatment of obesity and excess weight, as well as obstructive sleep apnea syndrome in obese individuals

This worsens the oxidative stress and finally leads to DNA damages (Stermann et al., 2022)