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Semaglutide injections work best when placed correctly into subcutaneous tissue, and your thigh offers a large, accessible injection site that many patients prefer

Specifically hormonal IUDs (Mirena, Kyleena, Skyla) and the subdermal implant (Nexplanon)

Martnez-Esparza M, Jimnez-Cervantes C, Solano F, Lozano J, Garca-Borrn J

Ongoing studies of the safety and efficacy of chronic treatment with obesity medications will be important for the management of patients with MC4R deficiency and other clinical groups