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No statistically significant association was detected for the risk of NAFLD with any other biomarkers tested, including TMA and choline (Table 2)

A multicenter international trial (KEYNOTE 006 [NCT01866319]) randomly assigned 834 patients with metastatic melanoma in a 1:1:1 ratio to receive pembrolizumab (10 mg/kg IV every 2 weeks or every 3 weeks) or four cycles of ipilimumab (3 mg/kg every 3 weeks).[2] Patients were stratified by ECOG PS (0 vs

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These include the release of lipid mediators, as well as a role in aspirin resistance under certain conditions, such as in patients after coronary artery bypass graft surgery [94]

There are no known direct interactions between NAD precursors and tirzepatide injection