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6 and 7), indicating that metformin likely exerts at least part of its chondroprotective effects by activating the Nrf2 signaling pathway

Concentrations were then corrected for these with the following formula: where [Mcorr] is the corrected concentration, [M] is the water-referenced metabolite concentration from the LCmodel output, fCSF is CSF fraction in the voxel, fGM is GM fraction in the voxel, and fWM is GM fraction in the voxel

To facilitate these investigations, the Federal Bureau of Investigation (FBI) launched the Innocence Lost program in 2003