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Think of it this way: Methylmalonic acid (MMA) is a metabolic byproduct that accumulates in the body when there isn't enough active vitamin B12 to break it down

Strategies aimed at restoring glutathione homeostasis or reducing oxidative and inflammatory stress could also be explored as possible complements to existing TTR-targeted therapies

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4.4 SCFAs improve oxidative stress Oxidative stress is a state of loss of balance between the oxidative and antioxidant systems of cells and tissues, and the process leads to the overproduction of oxidative free radicals and reactive oxygen species (ROS), destroying cellular proteins, lipids and nucleic acids, leading to cellular dysfunction (Rani et al., 2016)

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