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The release of IL-1 and TNF- can lead to a reduction in the expression of TJs and facilitate the engulfment of ECs by microglial cells [133, 134]

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Tras la reconstitucin del pptido debe almacenarse a 4 C entre 2-21 das y para el uso futuro por debajo de -18 C

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Participants were allocated in a 21:3:3:7 ratio to weekly injections of one of four regimens: fixed-dose cagrilintide 2.4 mg plus semaglutide 2.4 mg, semaglutide alone, cagrilintide alone, or placebo