eumelanin offers better UV protection Proliferation of melanocytes in long-term exposure Skin darkening (= tanning without UV) This mechanism is why Melanotan II causes visible skin pigmentation already after a few doses
These reports indicate that there might be a major genetic component to the anti-oxidant defense systems of cells
Too many tannins can be very astringent and irritating to the skin, so this is not necessarily a bad thing
The researchers concluded that "these findings agree with previous observations among healthy adult subjects and demonstrate that L-carnitine L-tartrate supplementation beyond 35 days is beneficial for improving recovery and reducing fatigue following exercise across gender and age." Of course none of this comes as a surprise to members of the ProSource Product Research Team
Metabolism & Elimination The metabolic fate of Syn-AKE remains incompletely characterized, though general peptide degradation pathways likely apply: Enzymatic degradation through peptidases in skin tissue and systemic circulation Rapid clearance expected based on small peptide structure Half-life estimates not well-established in human studies Minimal systemic accumulation expected with topical application A notable characteristic is the duration-potency disconnect : despite presumed rapid peptide degradation, effects on muscle contractility persist for hours after single applications and cumulative effects develop over weeks, suggesting either tissue retention, formation of active metabolites, or triggering of persistent signaling cascades
