Weight management, long-term (Saxenda) Mechanism: GLP-1 receptor agonist Dynamic interactions: Glucose lowering Kinetic interactions: Delayed gastric emptying, otherwise none in a bubble Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist available as a once-daily subcutaneous injectable
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A cohort study found that GLP-1RAs were associated with a reduced risk of hepatic decompensation and mortality in individuals with type 2 diabetes cirrhosis (Yen et al., 2024)
ClinicalTrials.gov: NCT04881760 (Phase 2, Obesity), NCT04867785 (Phase 2, T2D) Questions to ask your doctor Given my health history, is a GLP-1 medication appropriate for me at all
A better contraction of human atria due to dulaglutide should lead to better filling of the ventricles and hence to better cardiac output in patients with heart failure (Jrvinen et al