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This is particularly relevant in neurodegenerative diseases, where oxidative phosphorylation can be impaired

Semaglutide Functions primarily as a GLP-1 receptor agonist Helps regulate appetite and satiety Widely used in medical weight-loss programs Tirzepatide Targets both GLP-1 and GIP pathways Provides dual hormone activity May produce greater average weight loss in some patients The best option depends on several factors, including medical history, treatment goals, medication tolerance, and provider recommendations

Following one year of treatment, BMI decreased by an average of 0.55 kg/m 2 in the ORLISTAT-treated patients and increased by an average of 0.31 kg/m 2 in the placebo-treated patients (p=0.001)

Have a BMI of 30 or above

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