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Shabani E, Sayemiri K, Mohammadpour M
The cost barrier is equally structural: at USD 1,000-1,300 per month without insurance, GLP-1 drugs are affordable only to a small fraction of the global population who could benefit clinically, concentrating commercial market growth in the wealthy minority of the total addressable patient population
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OAD=oral antihyperglycemic drugs
Compared to peptide GLP- 1 receptor agonists, orforglipron, exhibits less receptor desensitization by increasing cyclic AMP signaling [105]
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