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Translational studies using exosomes showed a relationship between the epigenetic modulation of glutamatergic function and a brain metabolic dysfunction known as insulin resistance (IR) as showed by an increase and sex-specific phosphorylation in the expression of IRS1, a key marker of the insulin signaling cascade, in discrete exosomes enriched for the neural cell adhesion molecule L1 (L1CAM), a protein highly expressed in the brain [52, 70,71,72]

Taking vitamin B12 on your own can cause serious problems

YFF25001838 and No

2017a;00419:2016

doi:10.1038/s41569-023-00849-3 Wang W, Volkow ND, Berger NA, Davis PB, Kaelber DC, Xu R