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Adipose tissue with the unique capacity to produce heat by consuming circulatory and intracellularly stored substrates is commonly known as brown adipose tissue (BAT)

The prevalence of NAFLD in the general population ranges from 10 to 24% [2,3,4,5]

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Semaglutide, one of the most widely prescribed weight loss injections, has been studied extensively in clinical trials

Mechanistic studies revealed that this compound reduced UVB-induced reactive oxygen species (ROS) generation, decreased the proportion of apoptotic cells, and enhanced autophagic flux as evidenced by increased LC3-II accumulation and decreased p62 expression [1]