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Researchers studied AOD-9604 to see whether the fat-metabolism part of growth hormone could work without the muscle-building, blood-sugar, and IGF-1 effects of the full hormone

The higher dose in the second half of the cycle is designed to reinforce the collagen synthesis, sirtuin activation, and anti-inflammatory pathways initiated in Phase 1

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Fico A, Paglialunga F, Cigliano L, Abrescia P, Verde P, Martini G et al

For anyone exploring the difference between microdosing tirzepatide and standard dosing, the SURMOUNT data makes it clear that sub-therapeutic doses below 5 mg produce minimal weight loss