According to NICE guidance (NG28), GLP-1 receptor agonists like Rybelsus may be considered as part of treatment regimens when other therapies have not achieved adequate glycaemic control, particularly in patients with specific needs around weight management or cardiovascular risk
Other medications that can affect B12 absorption include colchicine, phenobarbital, pregabalin, primidone, topiramate and H2-receptor antagonists
That may sound modest, but it represents a breakthrough for a class of drugs typically given by injection
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59 , 60 , 61 , 62 The reversible oxidative modifications of cysteine residues imply an important mechanism whereby ROS and RNS can readily interact with these molecules, dictating protein function and cell signaling that can be regulated by GSH