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This long half-life is the primary reason it is suitable for a once-weekly dosing regimen, as it allows for the maintenance of steady-state therapeutic concentrations throughout the dosing interval

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Furthermore, Sun et al., showed that HuSC-Exos protect against kidney ischemia-reperfusion injury by reducing ferroptosis via lncRNA taurine upregulated gene 1, which regulates ACSL4 through serine arginine-rich splicing factor 1 interaction, suggesting a potential acute kidney injury therapy [72, 106] (Table 1)

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