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In these patients, administration of an NSAID may cause a dose-dependant reduction in prostaglandin formation and, secondarily, in renal blood flow, which may precipitate overt renal failure

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BPC-157 also influences the expression of additional growth factors including epidermal growth factor (EGF), basic fibroblast growth factor (bFGF), and the early growth response gene EGR-1

These usually resolve without intervention within 48 hours

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