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MS immunopathology is characterized by peripheral immune activation, breach of the BBB, and infiltration of immune cells into the CNS, followed by an interplay of innate and adaptive immune responses that damage myelin and axons (47, 116)
Medical research shows that abrupt cessation differs significantly from planned dose reduction, making the decision to stop GLP-1 therapy one that requires careful clinical consideration rather than an immediate halt
After PS matching, no differences were observed in age, sex, height, weight, BMI, eGFR, smoking status, alcohol consumption, or the number of health screening examinations among the three groups
Pessah-Pollack do not recommend using GLP-1s during pregnancy