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A preclinical pilot study in human patients with chronic pain episodes found, that DSIP significantly reduced pain perception, also improved mood by reduction of depressive states, and that it may potentially be of interest for research into physiological addiction on pain medications, as it was observed to reduce withdrawal symptoms that occurs after discontinuation of long-term analgesic treatment

doi:10.1073/pnas.1002178107, PMID: 20713697 Adam-Vizi V, Chinopoulos C (2006) Bioenergetics and the formation of mitochondrial reactive oxygen species

Dosing Protocols and Administration Considerations BPC-157 dosing in published rodent studies typically ranges from 1020 micrograms per kilogram of body weight daily, administered subcutaneously

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