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But over time, these toxic chemicals can build up and cause a variety of serious conditions, including cancer, heart disease, and even arthritis

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Pending successful completion, FDA approval could come as early as 2027, which would make retatrutide the first approved triple-agonist medication

Biochem J 320:100510, PMID: 9003392 Nikulina MA, Andersen HU, Karlsen AE, Darville MI, Eizirik DL, Mandrup-Poluson T (2000) Glutathione depletion inhibits interleukin 1 beta-stimulated nitric oxide production by reducing inducible nitric oxide synthase gene expression