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Dietary modifications represent the first-line approach to managing indigestion: Eat smaller, more frequent meals rather than large portions, which can overwhelm the already-slowed digestive system Avoid high-fat foods , as fats delay gastric emptying further and may exacerbate symptoms Limit spicy, acidic, or heavily seasoned foods that can irritate the upper gastrointestinal tract Reduce carbonated beverages and caffeine , which may increase bloating and gastric discomfort Eat slowly and chew thoroughly to facilitate digestion and reduce the burden on the stomach Avoid lying down immediately after meals

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Glucose-dependent insulinotropic polypeptide receptor signaling alleviates gut inflammation in mice

Am Heart J 267:111

Getting it wrong degrades the medication before you use it