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Patients should be advised that NHS-funded treatment duration is typically limited to a maximum of 2 years, as per NICE guidance, and that discontinuation often results in weight regain

The majority of the published data is still preclinical, and there are still plenty of issues concerning the safety, pharmacology and effectiveness of the use of BPC-157 to be answered

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Keywords: Parkinson disease, glucagon-like peptide-1, exendin-4, exenatide, neuroinflammation, neuroprotection, neurogenesis, neurotrophic, gutbrain axis Introduction Neurodegenerative disorders generally show a mixture of abnormal motor and cognitive function and are characterized by a selective type of neurological pathology, derived from quite distinct areas of the brain