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Incretins have been studied for more than 140 years, but advancements in the 2010s and 2020s highlight two: GIP (glucose-dependent insulinotropic polypeptide), from the upper gut, and GLP-1 (glucagon-like peptide-1), from the lower gut
GLP-1s represent a powerful tool to improve health outcomes, but they are not a guaranteed solution
Only in the last year or two have GLP-1s even inched into that company
More than 50 genes have been linked to ALS, with the most common being C9ORF72, which causes up to 50% of inherited cases and 510% of sporadic ones
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