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For researchers running extended caloric deficits (2030% below maintenance), this timing prevents the muscle loss that typically accompanies aggressive fat loss protocols

Tsay HJ, Wang P, Wang SL, Ku HH (2000) Age-associated changes of superoxide dismutase and catalase activities in the rat brain

However, no significant effect was observed on the rates of heart failure or myocardial reinfarction (DiNicolantonio et al

Youll also want to work with a doctor who can monitor your health, explain the research, and help you make decisions based on medical evidence, not just glowing testimonials on TikTok