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One consistent pattern of pathology has emerged: there is a strong association of demyelination with proximity to CSF-containing spaces, including the subpial cortex, CSF-filled perivascular Virchow-Robin spaces (part of the brains glymphatic system

Draw the appropriate amount of bacteriostatic water into a syringe, then slowly inject it down the inside wall of the vial rather than directly onto the powder

Some require particular modifications to show that the injection differs from other services delivered during the same visit

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Atomic coordinates referenced in the main text can be found through 1B33, 3MWN