Human data: Human evidence is limited to a single published Phase I/II pharmacokinetic-pharmacodynamic dose-escalation study in healthy adults
Y = years, mg = milligrams, mcg = micrograms, n = number of subjects, BMI = body mass index, NASH = non-alcoholic steatohepatitis, NAFLD = non-alcoholic fatty liver disease, kg = kilograms, ALT = alanine aminotransferase, AST = aspartate transaminase, LFF = liver fat fraction, T2DM = type 2 diabetes mellitus, PCOS = polycystic ovary syndrome, NR = not reported
P6403, Sigma-Aldrich) 96-well white polystyrene LumiNunc plates (catalogue no
Guarantee healing: Individual variation means some people respond excellently while others show minimal benefits
Some take longer, up to 30 minutes in rare cases