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doi:10.1095/biolreprod.115.130658

Los ratones que carecen de GCLC (es decir, todas las sntesis de nuevo GSH) mueren antes de nacer

Cytosolic and nuclear NAD + are often considered a shared pool as NAD + diffuses through nuclear pores 58 , and importantly, the concentrations of NAD + in the cytosol, nucleus, and mitochondria mirror the K m of NAD + -consuming enzymes localized to the corresponding compartment, hence these enzymes are sensitive to compartmental fluctuations in NAD + levels 77

In addition to their functions in cell proliferation and differentiation, omega-3 and omega-6 fatty acids are also important for suppressing inflammation and regulating the immune system

Cheng X, Xie Q, Sun Y